全文获取类型
收费全文 | 36063篇 |
免费 | 2045篇 |
国内免费 | 150篇 |
专业分类
耳鼻咽喉 | 397篇 |
儿科学 | 1300篇 |
妇产科学 | 995篇 |
基础医学 | 5006篇 |
口腔科学 | 949篇 |
临床医学 | 3442篇 |
内科学 | 7584篇 |
皮肤病学 | 767篇 |
神经病学 | 3458篇 |
特种医学 | 1414篇 |
外科学 | 4519篇 |
综合类 | 196篇 |
现状与发展 | 1篇 |
一般理论 | 12篇 |
预防医学 | 2885篇 |
眼科学 | 653篇 |
药学 | 2553篇 |
中国医学 | 104篇 |
肿瘤学 | 2023篇 |
出版年
2023年 | 293篇 |
2022年 | 190篇 |
2021年 | 783篇 |
2020年 | 535篇 |
2019年 | 764篇 |
2018年 | 1139篇 |
2017年 | 854篇 |
2016年 | 886篇 |
2015年 | 895篇 |
2014年 | 1119篇 |
2013年 | 1695篇 |
2012年 | 2539篇 |
2011年 | 2580篇 |
2010年 | 1331篇 |
2009年 | 1155篇 |
2008年 | 2117篇 |
2007年 | 2267篇 |
2006年 | 2171篇 |
2005年 | 2159篇 |
2004年 | 1952篇 |
2003年 | 1942篇 |
2002年 | 1811篇 |
2001年 | 728篇 |
2000年 | 767篇 |
1999年 | 606篇 |
1998年 | 258篇 |
1997年 | 234篇 |
1996年 | 243篇 |
1995年 | 215篇 |
1994年 | 201篇 |
1993年 | 165篇 |
1992年 | 308篇 |
1991年 | 279篇 |
1990年 | 232篇 |
1989年 | 269篇 |
1988年 | 212篇 |
1987年 | 236篇 |
1986年 | 226篇 |
1985年 | 217篇 |
1984年 | 126篇 |
1983年 | 115篇 |
1982年 | 95篇 |
1981年 | 79篇 |
1980年 | 70篇 |
1979年 | 119篇 |
1978年 | 85篇 |
1977年 | 95篇 |
1976年 | 71篇 |
1975年 | 91篇 |
1974年 | 85篇 |
排序方式: 共有10000条查询结果,搜索用时 125 毫秒
31.
32.
Relation of Epicardial Fat Thickness to Subclinical Right Ventricular Dysfunction Assessed by Strain and Strain Rate Imaging in Subjects with Metabolic Syndrome: A Two‐Dimensional Speckle Tracking Echocardiography Study 下载免费PDF全文
33.
34.
35.
36.
Imre W.K. Kouw Bart B.L. Groen Joey S.J. Smeets Irene Fleur Kramer Janneau M.X. van Kranenburg Rachél Nilwik Jan A.P. Geurts René H.M. ten Broeke Martijn Poeze Luc J.C. van Loon Lex B. Verdijk 《Journal of the American Medical Directors Association》2019,20(1):35-42
Objectives
Short successive periods of skeletal muscle disuse have been suggested to substantially contribute to the observed loss of skeletal muscle mass over the life span. Hospitalization of older individuals due to acute illness, injury, or major surgery generally results in a mean hospital stay of 5 to 7 days, during which the level of physical activity is strongly reduced. We hypothesized that hospitalization following elective total hip arthroplasty is accompanied by substantial leg muscle atrophy in older men and women.Design and participants
Twenty-six older patients (75 ± 1 years) undergoing elective total hip arthroplasty participated in this observational study.Measurements
On hospital admission and on the day of discharge, computed tomographic (CT) scans were performed to assess muscle cross-sectional area (CSA) of both legs. During surgery and on the day of hospital discharge, a skeletal muscle biopsy was taken from the m. vastus lateralis of the operated leg to assess muscle fiber type–specific CSA.Results
An average of 5.6 ± 0.3 days of hospitalization resulted in a significant decline in quadriceps (?3.4% ± 1.0%) and thigh muscle CSA (?4.2% ± 1.1%) in the nonoperated leg (P < .05). Edema resulted in a 10.3% ± 1.7% increase in leg CSA in the operated leg (P < .05). At hospital admission, muscle fiber CSA was smaller in the type II vs type I fibers (3326 ± 253 μm2 vs 4075 ± 279 μm2, respectively; P < .05). During hospitalization, type I and II muscle fiber CSA tended to increase, likely due to edema in the operated leg (P = .10).Conclusions
Six days of hospitalization following elective total hip arthroplasty leads to substantial leg muscle atrophy in older patients. Effective intervention strategies are warranted to prevent the loss of muscle mass induced by short periods of muscle disuse during hospitalization. 相似文献37.
Joël Greffier Djamel Dabli Aymeric Hamard Philippe Akessoul Asmaa Belaouni Jean-Paul Beregi Julien Frandon 《Diagnostic and interventional imaging》2021,102(7-8):405-412
PurposeTo assess the impact of dose reduction and the use of an advanced modeled iterative reconstruction algorithm (ADMIRE) on image quality in low-energy monochromatic images from a dual-source dual energy computed tomography CT (DSCT) platform.Materials and methodsAcquisitions on an image-quality phantom were performed using DSCT equipment with 100/Sn150 kVp for four dose levels (CTDIvol: 20/11/8/5mGy). Raw data were reconstructed for six energy levels (40/50/60/70/80/100 keV) using filtered back projection and two levels of ADMIRE (A3/A5). Noise power spectrum (NPS) and task-based transfer function (TTF) were calculated on virtual monoenergetic images (VMIs). Detectability index (d′) was computed to model the detection task of two enhanced iodine lesions as function of keV.ResultsNoise-magnitude was significantly reduced between 40 to 70 keV by ?56 ± 0% (SD) (range: ?56%–?55%) with FBP; ?56 ± 0% (SD) (?56%–?56%) with A3; and ?57 ± 1% (SD) (range: ?57%–?56%) with A5. The average spatial frequency of the NPS peaked at 70 keV and decreased as ADMIRE level increased. TTF values at 50% were greatest at 40 keV and shifted towards lower frequencies as the keV increased. The detectability of both lesions increased with increasing dose level and ADMIRE level. For the simulated lesion with iodine at 2 mg/mL, d’ values peaked at 70 keV for all reconstruction types, except for A3 at 20 mGy and A5 at 11 and 20 mGy, where d’ peaked at 60 keV. For the other simulated lesion, d’ values were highest at 40 keV and decreased beyond.ConclusionAt low keV on VMIs, this study confirms that iterative reconstruction reduces the noise magnitude, improves the spatial resolution and increases the detectability of enhanced iodine lesions. 相似文献
38.
Orhan Görgülü Feride Fatma Görgülü Ayşe Selcan Koç 《Revista brasileira de otorrinolaringologia (English ed.)》2021,87(3):338-345
IntroductionOnly 5%–15% of thyroid surgical specimens are reported as malignant. Most of the operations are performed due to suspicion of malignancy as a result of fine needle aspiration biopsy but invasiveness, non-diagnostic results and potential repeat biopsies are disadvantages of fine needle aspiration biopsy.ObjectiveThe aim of this study was to investigate the effectiveness of simultaneously using both the strain ratio and elasticity score in the differential diagnosis of thyroid nodules, as well as to assess the compatibility of these two methods.MethodsA total of 144 nodules were included in the study. The final histopathologic diagnosis was used as the reference standard. The area under the curve sensitivity, specificity, and cut-off values of the strain ratio and elasticity score were determined using receiver operating characteristic curve analysis. The compatibility and comparison of strain ratio and elasticity score were also performed.ResultsTwenty eight nodules (19.4%) were malignant. The strain ratio and elasticity score results were found to be significantly successful in predicting thyroid malignancy (p < 0.001 for both). Moreover, the area under the curve for the strain ratio and elasticity score were found to be 0.944 and 0.960, respectively. The diagnostic accuracy of the elasticity score was found to be superior to that of the strain ratio, but this difference was not statistically significant (p = 0.456). When the compatibility of the strain ratio and elasticity score was examined, the two evaluations were revealed to be statistically consistent with each other (Kappa = 0.767; p < 0.001). When the strain ratio and the elasticity score were used together, the specificity of capturing the correct diagnosis increased from 84.5% to 93.1%.ConclusionWhen the strain ratio an elasticity score were used together for the differential diagnosis of thyroid nodules, more accurate results were obtained. Thus, combining both methods may be a promising alternative to fine needle aspiration biopsy in order to prevent unnecessary surgical interventions for suspected thyroid nodules. 相似文献
39.
Jérôme Le Pavec Séverine Feuillet Olaf Mercier Pauline Pradère Gaëlle Dauriat Adrian Crutu Valentina Florea Laurent Savale Marilyne Levy Florent Laverdure François Stephan Dominique Fabre Mitilian Delphine David Boulate Sacha Mussot Sébastien Hascoët Damien Bonnet Marc Humbert Elie Fadel 《The Journal of heart and lung transplantation》2021,40(7):652-661
40.